PPIAP51

Across TCGA patient cohorts, PPIAP51 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,796 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAP51-associated GO terms across cancer lineages are Regulation of binding, Chaperone-mediated protein folding, and Regulation of cysteine-type endopeptidase activity involved in apoptotic process. Each is linked with PPIAP51 in more than 21 cancer types. Because this analysis shows association rather than direction, both PPIAP51-to-partner and partner-to-PPIAP51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of binding grouped by PPIAP51-low versus PPIAP51-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP51→partner) and Y-score (partner→PPIAP51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of binding →	+0.041	+0.446	<.001	<.001	3	22
STAD	Chaperone-mediated protein folding →	+0.053	+0.353	<.001	<.001	3	22
STAD	Regulation of cysteine-type endopeptidase activity involved in apoptotic process →	+0.044	+0.411	<.001	<.001	3	22
STAD	Positive regulation of cysteine-type endopeptidase activity →	+0.038	+0.422	<.001	<.001	3	21
ESCA	Regulation of DNA binding →	+0.037	+0.369	<.001	<.001	3	21
STAD	Positive regulation of post-translational protein modification →	+0.044	+0.352	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,796 associations by consensus.

Regulation of binding by PPIAP51 expression — STAD

Explore this box plot interactively →