PPIAP5

Across TCGA patient cohorts, PPIAP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,284 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAP5-associated GO terms across cancer lineages are NADH dehydrogenase complex assembly, Glycosyl compound metabolic process, and Negative regulation of ryanodine-sensitive calcium-release channel activity. Each is linked with PPIAP5 in more than 7 cancer types. Because this analysis shows association rather than direction, both PPIAP5-to-partner and partner-to-PPIAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NADH dehydrogenase complex assembly grouped by PPIAP5-low versus PPIAP5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP5→partner) and Y-score (partner→PPIAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	NADH dehydrogenase complex assembly →	+0.053	+0.080	<.001	.001	3	8
STAD	Glycosyl compound metabolic process →	+0.028	+0.096	<.001	<.001	3	8
COAD	Negative regulation of ryanodine-sensitive calcium-release channel activity →	+0.038	+0.038	<.001	.003	3	7
UCEC	Protein K11-linked ubiquitination →	+0.046	+0.040	<.001	<.001	3	7
STAD	Mitochondrial gene expression →	+0.040	+0.055	<.001	.001	2	8
STAD	RNA modification →	+0.037	+0.074	<.001	.002	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,284 associations by consensus.

NADH dehydrogenase complex assembly by PPIAP5 expression — STAD

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