peptidylprolyl isomerase A pseudogene 40Genealiases: []
Q-omics provides the consensus-scored PPIAP40 profile across patient tissues and cancer cell-line models. PPIAP40 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, PPIAP40 is differentially expressed in 10, with the highest sampling consensus in KIRP. Additionally, PPIAP40 RNA expression shows 12,175 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, KIRP, and THYM as cancer lineages where PPIAP40 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PPIAP40 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PPIAP40 survival associations across molecular data types. PPIAP40 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PPIAP40 RNA expression–survival associations across cancer types. High PPIAP40 expression shows unfavorable associations in KIRC, UVM, ACC and KIRP, but favorable associations in CESC and LUSC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for PPIAP40 RNA expression.
This table summarizes PPIAP40 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for PPIAP40. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PPIAP40 shows higher tumor expression in KIRP, STAD, LUAD, CHOL, BRCA and LIHC. The KIRP box plot shows higher PPIAP40 RNA expression in tumor versus normal tissue (log2 FC = +0.338, t-test p = .001).
This table shows molecular features associated with PPIAP40 in patient tissues and cancer cell lines. In patient samples, PPIAP40 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
