PPIAP4

Across TCGA pan-cancer cohorts, PPIAP4 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated PPIAP4 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher PPIAP4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PPIAP4 expression acts as an unfavorable survival marker, although some lineages such as BLCA and KIRP show a favorable association.

BLCA, KIRP, and ACC are the cancer types where PPIAP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	II,III,IV	0.676	0.538	.001	74	view →
KIRP	OS	Tertile	All	0.819	0.584	.006	65	view →
ACC	OS	Quartile	All	0.258	0.895	.002	45	view →
OV	DFS	Tertile	All	0.604	0.494	.008	32	view →
READ	OS	Median	III,IV	0.724	0.265	.001	25	view →
KIRC	DFS	Quartile	II,III,IV	0.375	0.614	.014	20	view →
CHOL	OS	Quartile	II,III,IV	0.948	0.210	.004	12	view →
UVM	OS	Median	III,IV	0.296	1.000	.005	11	view →
HNSC	DFS	Tertile	II,III,IV	0.639	0.773	.008	10	view →
LIHC	OS	Tertile	II,III,IV	0.378	0.563	.017	7	view →
SKCM	OS	Tertile	III,IV	0.762	0.600	.015	6	view →
LGG	OS	Median	All	0.957	0.854	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

PPIAP4–BLCA (OS)

Open the BLCA breakdown →