PPIAP36

Across TCGA pan-cancer cohorts, PPIAP36 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PPIAP36 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PPIAP36 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPIAP36 expression acts as an unfavorable survival marker, although some lineages such as READ and ESCA show a favorable association.

UVM, READ, and UCEC are the cancer types where PPIAP36 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.402	0.834	<.001	126	view →
READ	OS	Median	All	0.815	0.309	<.001	98	view →
UCEC	DFS	Tertile	III,IV	0.665	0.851	<.001	78	view →
ESCA	OS	Tertile	III,IV	0.616	0.282	.008	27	view →
STAD	DFS	Tertile	II,III,IV	0.506	0.767	.007	24	view →
COAD	DFS	Median	All	0.422	0.580	.008	23	view →
TGCT	DFS	Tertile	All	0.734	0.881	.017	14	view →
ACC	OS	Tertile	IV	0.850	0.221	.017	12	view →
CHOL	OS	Tertile	II,III,IV	1.000	0.504	.038	9	view →
DLBC	DFS	Quartile	III,IV	0.308	0.849	.032	9	view →
BRCA	OS	Tertile	All	0.431	0.625	.019	9	view →
KIRP	OS	Median	All	0.959	0.814	.034	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

PPIAP36–UVM (DFS)

Open the UVM breakdown →