PPIAP35

Across TCGA patient cohorts, PPIAP35 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,305 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPIAP35-associated proteins across cancer lineages are TSPYL5, PUM1, and TTC4. Each is linked with PPIAP35 in more than 3 cancer types. Because this analysis shows association rather than direction, both PPIAP35-to-partner and partner-to-PPIAP35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIAP35 versus TSPYL5 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP35→partner) and Y-score (partner→PPIAP35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TSPYL5 →	+1.131	+0.764	<.001	<.001	3	4
OV	PUM1 →	+0.223	+0.725	.001	<.001	3	4
OV	TTC4 →	+0.260	+0.555	.001	<.001	3	3
UCEC	PBXIP1 →	+0.562	+0.487	.001	<.001	3	3
OV	PIGS →	+0.319	+0.735	<.001	<.001	3	3
CCRCC	NUP88_S517 →	+0.397	+0.196	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,305 associations by consensus.

PPIAP35 vs TSPYL5 — BRCA

Explore this scatter interactively →