PPIAP33

Across TCGA patient cohorts, PPIAP33 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,609 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAP33-associated GO terms across cancer lineages are [2Fe-2S] cluster assembly, Ribosomal large subunit assembly, and Protein maturation by iron-sulfur cluster transfer. Each is linked with PPIAP33 in more than 17 cancer types. Because this analysis shows association rather than direction, both PPIAP33-to-partner and partner-to-PPIAP33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [2Fe-2S] cluster assembly grouped by PPIAP33-low versus PPIAP33-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP33→partner) and Y-score (partner→PPIAP33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	[2Fe-2S] cluster assembly →	+0.060	+0.383	<.001	<.001	3	18
STAD	Ribosomal large subunit assembly →	+0.054	+0.331	<.001	<.001	3	18
STAD	Protein maturation by iron-sulfur cluster transfer →	+0.060	+0.385	<.001	<.001	3	17
OV	Protein K29-linked ubiquitination →	+0.045	+0.149	<.001	<.001	3	16
ESCA	Outer mitochondrial membrane organization →	+0.060	+0.414	.003	<.001	3	16
STAD	NADH dehydrogenase complex assembly →	+0.056	+0.344	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,609 associations by consensus.

[2Fe-2S] cluster assembly by PPIAP33 expression — DLBC

Explore this box plot interactively →