PPIAP3

Across TCGA patient cohorts, PPIAP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,231 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPIAP3-associated proteins across cancer lineages are RPRD1B, BEND3, and XAB2. Each is linked with PPIAP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PPIAP3-to-partner and partner-to-PPIAP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPIAP3 versus RPRD1B in LSCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP3→partner) and Y-score (partner→PPIAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPRD1B →	+0.353	+0.366	.001	.001	3	4
LSCC	BEND3 →	+0.333	+0.350	<.001	<.001	3	4
LSCC	XAB2 →	+0.221	+0.262	<.001	<.001	3	4
OV	NASP →	+0.689	+0.721	<.001	<.001	3	4
BRCA	CEBPZ →	+0.352	+0.500	<.001	.002	3	3
LSCC	ESF1 →	+0.275	+0.291	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,231 associations by consensus.

PPIAP3 vs RPRD1B — LSCC

Explore this scatter interactively →