PPIAP25

Across TCGA patient cohorts, PPIAP25 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,220 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAP25-associated GO terms across cancer lineages are Ribosomal large subunit assembly, Outer mitochondrial membrane organization, and Amino acid metabolic process. Each is linked with PPIAP25 in more than 13 cancer types. Because this analysis shows association rather than direction, both PPIAP25-to-partner and partner-to-PPIAP25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal large subunit assembly grouped by PPIAP25-low versus PPIAP25-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP25→partner) and Y-score (partner→PPIAP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ribosomal large subunit assembly →	+0.064	+0.249	<.001	<.001	3	14
STAD	Outer mitochondrial membrane organization →	+0.059	+0.249	<.001	<.001	3	14
STAD	Amino acid metabolic process →	+0.037	+0.244	<.001	<.001	3	14
STAD	tRNA 5'-end processing →	+0.045	+0.198	<.001	<.001	3	13
STAD	Respiratory electron transport chain →	+0.059	+0.193	<.001	<.001	3	13
STAD	Mitochondrial respiratory chain complex assembly →	+0.056	+0.220	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,220 associations by consensus.

Ribosomal large subunit assembly by PPIAP25 expression — STAD

Explore this box plot interactively →