Across TCGA pan-cancer cohorts, PPIAP22 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated PPIAP22 data layer compared with 29 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher PPIAP22 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP22 expression acts as an unfavorable survival marker.

BRCA are the cancer types where PPIAP22 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.115	0.578	.002	24	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: PPIAP22 tumor-vs-normal RNA expression · all PPIAP22 data types