Across TCGA patient cohorts, PPIAP22 RNA expression is significantly associated with the RNA expression of many other genes, with 19,470 significant associations in total. ACC shows the largest number of these associations.

The most reproducible PPIAP22-associated genes across cancer lineages are CHCHD3P3, TBRG4, and PPIA. Each is linked with PPIAP22 in more than 31 cancer types. Because this analysis shows association rather than direction, both PPIAP22-to-partner and partner-to-PPIAP22 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP22→partner) and Y-score (partner→PPIAP22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	CHCHD3P3 →	+0.703	+0.843	<.001	<.001	3	32
ACC	TBRG4 →	+0.830	+0.979	<.001	<.001	3	32
ACC	PPIA →	+1.310	+1.369	<.001	<.001	3	32
UVM	MRPL32 →	+1.010	+0.518	<.001	<.001	3	32
ACC	CBX3 →	+1.415	+1.227	<.001	<.001	3	32
READ	CYCS →	+1.138	+1.536	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,470 associations by consensus.

Exploration

PPIAP22 survival (RNA) · tumor vs normal (RNA) · all PPIAP22 data types