PPIAP20

Across TCGA pan-cancer cohorts, PPIAP20 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated PPIAP20 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PPIAP20 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP20 expression acts as an unfavorable survival marker, although some lineages such as READ and THYM show a favorable association.

UVM, MESO, and READ are the cancer types where PPIAP20 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	III,IV	0.037	0.809	<.001	33	view →
MESO	OS	Tertile	All	0.234	0.628	.003	30	view →
READ	DFS	Median	II,III,IV	0.960	0.629	.001	29	view →
LIHC	DFS	Tertile	All	0.336	0.589	<.001	27	view →
DLBC	DFS	Tertile	All	0.532	0.940	.010	21	view →
KIRC	DFS	Median	All	0.765	0.838	.008	20	view →
STAD	DFS	Quartile	IV	0.118	0.626	.002	18	view →
ESCA	OS	Median	II,III,IV	0.554	1.000	.021	12	view →
THYM	DFS	Median	III,IV	1.000	0.501	.018	10	view →
CESC	OS	Median	All	0.718	0.483	.017	10	view →
LUSC	DFS	Tertile	III,IV	0.424	0.204	.019	9	view →
LGG	DFS	Median	All	0.838	0.668	.001	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

PPIAP20–UVM (OS)

Open the UVM breakdown →