Across TCGA pan-cancer cohorts, PPIAP17 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of PPIAP17’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where PPIAP17 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PPIAP17 is over-expressed in tumor.
UCEC are the cancer types where PPIAP17 tumor–normal differential expression is most reproducible.