PPIAP15

Across TCGA pan-cancer cohorts, PPIAP15 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated PPIAP15 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PPIAP15 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP15 expression acts as an unfavorable survival marker, although some lineages such as THCA and THYM show a favorable association.

ACC, KICH, and OV are the cancer types where PPIAP15 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.469	0.773	<.001	88	view →
KICH	DFS	Tertile	II,III,IV	0.437	1.000	<.001	55	view →
OV	DFS	Quartile	All	0.291	0.433	<.001	52	view →
THCA	DFS	Median	III,IV	0.841	0.528	.003	29	view →
THYM	OS	Median	All	0.952	0.754	.007	25	view →
KIRC	DFS	Tertile	All	0.561	0.658	.020	15	view →
HNSC	DFS	Quartile	All	0.511	0.633	.016	14	view →
CESC	OS	Median	II,III,IV	0.701	0.400	.026	10	view →
UCEC	DFS	Median	All	0.858	0.922	.009	10	view →
READ	OS	Tertile	All	1.000	0.831	.036	7	view →
LUAD	OS	Tertile	All	0.757	0.843	.011	7	view →
LIHC	OS	Tertile	III,IV	0.664	0.226	.016	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

PPIAP15–ACC (OS)

Open the ACC breakdown →