PPIAP13

Across TCGA pan-cancer cohorts, PPIAP13 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PPIAP13 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher PPIAP13 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PPIAP13 expression acts as an unfavorable survival marker, although some lineages such as CESC and OV show a favorable association.

CESC, KICH, and UVM are the cancer types where PPIAP13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	II,III,IV	0.736	0.320	.001	88	view →
KICH	OS	Tertile	II,III,IV	0.844	1.000	.007	57	view →
UVM	OS	Median	III,IV	0.372	0.817	.007	42	view →
STAD	DFS	Tertile	II,III,IV	0.383	0.718	.005	38	view →
ACC	DFS	Quartile	All	0.479	0.816	.003	36	view →
LGG	DFS	Tertile	All	0.670	0.829	<.001	32	view →
OV	OS	Median	IV	0.488	0.252	.002	28	view →
KIRC	DFS	Tertile	IV	0.271	0.680	.024	14	view →
LIHC	DFS	Quartile	All	0.443	0.640	.001	12	view →
BRCA	OS	Tertile	All	0.951	0.973	.005	10	view →
KIRP	DFS	Median	II,III,IV	0.332	0.625	.024	10	view →
LUAD	DFS	Quartile	III,IV	0.620	0.229	.004	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PPIAP13–CESC (OS)

Open the CESC breakdown →