PPIAL4A

Across TCGA patient cohorts, PPIAL4A mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PPIAL4A-associated genes across cancer lineages are Erythrocytes, Th2 cells, and CD4+ Tem. Each is linked with PPIAL4A in more than 1 cancer types. Because this analysis shows association rather than direction, both PPIAL4A-to-partner and partner-to-PPIAL4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by PPIAL4A-low versus PPIAL4A-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAL4A→partner) and Y-score (partner→PPIAL4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Erythrocytes →	+0.019	+2.513	.009	.029	3	2
LUAD	Th2 cells →	+0.432	+2.819	<.001	.036	2	2
UCEC	CD4+ Tem →	+0.028	+3.496	<.001	.027	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Erythrocytes by PPIAL4A expression — LUAD

Explore this box plot interactively →