PPHLN1

Across TCGA cell cohorts, PPHLN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,164 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPHLN1-associated GO terms across cancer lineages are Nuclear transport, Nucleocytoplasmic transport, and Double-strand break repair via homologous recombination. Each is linked with PPHLN1 in more than 13 cancer types. Because this analysis shows association rather than direction, both PPHLN1-to-partner and partner-to-PPHLN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear transport grouped by PPHLN1-low versus PPHLN1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPHLN1→partner) and Y-score (partner→PPHLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Nuclear transport →	+0.080	+0.791	.001	<.001	3	14
BLOOD_Myeloma	Nucleocytoplasmic transport →	+0.079	+0.791	.001	<.001	3	14
OVARY	Double-strand break repair via homologous recombination →	+0.076	+0.457	<.001	.002	3	13
OVARY	Spindle elongation →	+0.200	+0.454	<.001	<.001	3	12
BLOOD_Lymphoma	Regulation of chromosome segregation →	+0.077	+0.655	<.001	<.001	3	12
BONE	Double-strand break repair →	+0.068	+0.503	.009	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,164 associations by consensus.

Nuclear transport by PPHLN1 expression — BLOOD_Myeloma

Explore this box plot interactively →