PPFIBP2

Across TCGA cell cohorts, PPFIBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,861 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PPFIBP2-associated GO terms across cancer lineages are Striatal medium spiny neuron differentiation, Monocarboxylic acid catabolic process, and Transport of virus. Each is linked with PPFIBP2 in more than 10 cancer types. Because this analysis shows association rather than direction, both PPFIBP2-to-partner and partner-to-PPFIBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Striatal medium spiny neuron differentiation grouped by PPFIBP2-low versus PPFIBP2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPFIBP2→partner) and Y-score (partner→PPFIBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Striatal medium spiny neuron differentiation →	-1.453	-2.523	<.001	.001	3	11
LIVER	Monocarboxylic acid catabolic process →	+0.066	+2.075	.001	<.001	3	11
BREAST	Transport of virus →	-0.187	-2.198	<.001	<.001	3	10
BLOOD_Lymphoma	Regulation of atrial cardiac muscle cell membrane repolarization →	-0.417	-2.440	.001	<.001	3	10
URINARY_TRACT	Serotonin transport →	+1.066	+2.442	<.001	<.001	3	10
OESOPHAGUS	Establishment of epithelial cell apical/basal polarity →	-0.210	-2.655	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,861 associations by consensus.

Striatal medium spiny neuron differentiation by PPFIBP2 expression — LIVER

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