PPFIA3

Across TCGA cell cohorts, PPFIA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,982 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPFIA3-associated GO terms across cancer lineages are ATP metabolic process, Regulation of short-term neuronal synaptic plasticity, and Aminoacyl-tRNA metabolism involved in translational fidelity. Each is linked with PPFIA3 in more than 13 cancer types. Because this analysis shows association rather than direction, both PPFIA3-to-partner and partner-to-PPFIA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP metabolic process grouped by PPFIA3-low versus PPFIA3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPFIA3→partner) and Y-score (partner→PPFIA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	ATP metabolic process →	+0.077	+1.792	.001	.001	3	14
LARGE_INTESTINE	Regulation of short-term neuronal synaptic plasticity →	+0.145	+1.119	<.001	<.001	3	14
BONE	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.112	+2.304	.005	<.001	3	13
SKIN	Nucleoside triphosphate metabolic process →	+0.088	+1.199	<.001	.001	3	13
SKIN	Purine nucleoside triphosphate metabolic process →	+0.083	+1.337	<.001	<.001	3	13
SOFT_TISSUE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.143	+1.794	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,982 associations by consensus.

ATP metabolic process by PPFIA3 expression — BONE

Explore this box plot interactively →