PPFIA2

Across TCGA cell cohorts, PPFIA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,526 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PPFIA2-associated GO terms across cancer lineages are Muscle system process, Antimicrobial peptide production, and Antimicrobial peptide biosynthetic process. Each is linked with PPFIA2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PPFIA2-to-partner and partner-to-PPFIA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Muscle system process grouped by PPFIA2-low versus PPFIA2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPFIA2→partner) and Y-score (partner→PPFIA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Muscle system process →	-0.039	-0.948	.001	.002	3	7
CNS	Antimicrobial peptide production →	-0.511	-0.941	.005	.005	3	6
CNS	Antimicrobial peptide biosynthetic process →	-0.511	-0.941	.005	.005	3	6
CNS	Antibacterial peptide production →	-0.511	-0.941	.005	.005	3	6
CNS	Antibacterial peptide biosynthetic process →	-0.511	-0.941	.005	.005	3	6
LUNG_SCLC	Amacrine cell differentiation →	+1.204	+2.108	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,526 associations by consensus.

Muscle system process by PPFIA2 expression — CNS

Explore this box plot interactively →