Q-omics provides the consensus-scored PPFIA1P1 profile across patient tissues and cancer cell-line models. PPFIA1P1 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, PPFIA1P1 is differentially expressed in 6, with the highest sampling consensus in STAD. Additionally, PPFIA1P1 RNA expression shows 12,858 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight THCA, STAD, and THYM as cancer lineages where PPFIA1P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PPFIA1P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PPFIA1P1 survival associations across molecular data types. PPFIA1P1 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PPFIA1P1 RNA expression–survival associations across cancer types. High PPFIA1P1 expression shows unfavorable associations in THCA, UVM and BLCA, but favorable associations in ACC, KIRP and CHOL. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for PPFIA1P1 RNA expression.
This table summarizes PPFIA1P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in STAD for RNA.
This table ranks reproducible tumor–normal expression differences for PPFIA1P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PPFIA1P1 shows lower tumor expression in UCEC and PAAD and higher tumor expression in STAD, BRCA, LUSC and KIRC. The STAD box plot shows higher PPFIA1P1 RNA expression in tumor versus normal tissue (log2 FC = +0.083, t-test p = .002).
This table shows molecular features associated with PPFIA1P1 in patient tissues and cancer cell lines. In patient samples, PPFIA1P1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
