PPFIA1

Across TCGA patient cohorts, PPFIA1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,695 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PPFIA1-associated genes across cancer lineages are FADD, CCND1, and PELI3. Each is linked with PPFIA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PPFIA1-to-partner and partner-to-PPFIA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPFIA1 versus FADD in HNSC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPFIA1→partner) and Y-score (partner→PPFIA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FADD →	+1.379	+0.910	<.001	<.001	3	5
HNSC	CCND1 →	+1.648	+0.744	<.001	<.001	3	4
BRCA	PELI3 →	+0.350	+0.224	.003	.001	3	4
HNSC	MRPL21 →	+1.485	+0.902	<.001	<.001	3	4
HNSC	H2AZP4 →	+1.599	+0.902	<.001	<.001	3	4
HNSC	CTTN →	+1.485	+0.859	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,695 associations by consensus.

PPFIA1 vs FADD — HNSC

Explore this scatter interactively →