PPFIA1

Across TCGA cell cohorts, PPFIA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,222 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPFIA1-associated GO terms across cancer lineages are Cortical microtubule organization, Regulation of mRNA processing, and Phosphatidylinositol biosynthetic process. Each is linked with PPFIA1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PPFIA1-to-partner and partner-to-PPFIA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cortical microtubule organization grouped by PPFIA1-low versus PPFIA1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPFIA1→partner) and Y-score (partner→PPFIA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Cortical microtubule organization →	+0.132	+0.623	<.001	<.001	3	15
BLOOD_Lymphoma	Regulation of mRNA processing →	+0.079	+0.774	<.001	.001	3	14
LARGE_INTESTINE	Phosphatidylinositol biosynthetic process →	+0.061	+0.946	<.001	<.001	3	14
LARGE_INTESTINE	Vacuolar transport →	+0.058	+0.972	<.001	<.001	3	14
BLOOD_Lymphoma	Regulation of DNA-templated transcription initiation →	+0.063	+0.824	<.001	<.001	3	14
OESOPHAGUS	Regulatory ncRNA-mediated gene silencing →	+0.127	+2.441	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,222 associations by consensus.

Cortical microtubule organization by PPFIA1 expression — BLOOD_Leukemia

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