PPEF1-AS1

Across TCGA pan-cancer cohorts, PPEF1-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated PPEF1-AS1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher PPEF1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPEF1-AS1 expression acts as an unfavorable survival marker.

THCA, BLCA, and KIRC are the cancer types where PPEF1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	All	0.493	0.833	<.001	81	view →
BLCA	OS	Tertile	All	0.141	0.687	.003	54	view →
KIRC	OS	Tertile	II,III,IV	0.344	0.557	.004	48	view →
READ	DFS	Tertile	III,IV	0.255	0.757	.008	45	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
UCEC	DFS	Tertile	All	0.688	0.843	.032	18	view →
UVM	OS	Tertile	All	0.693	0.919	.028	15	view →
KIRP	OS	Tertile	All	0.849	0.950	.013	12	view →
GBM	OS	Tertile	All	0.189	0.431	.002	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
PCPG	DFS	Tertile	All	0.391	0.857	.048	9	view →
THYM	OS	Tertile	All	0.612	0.920	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

PPEF1-AS1–THCA (DFS)

Open the THCA breakdown →