PPCS

Across TCGA cell cohorts, PPCS RNA expression is significantly associated with the go_rna of many other GO terms, with 4,040 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPCS-associated GO terms across cancer lineages are Sperm motility, 'de novo' IMP biosynthetic process, and Flagellated sperm motility. Each is linked with PPCS in more than 9 cancer types. Because this analysis shows association rather than direction, both PPCS-to-partner and partner-to-PPCS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm motility grouped by PPCS-low versus PPCS-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPCS→partner) and Y-score (partner→PPCS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Sperm motility →	-0.081	-0.915	<.001	<.001	3	10
LUNG_SCLC	'de novo' IMP biosynthetic process →	-0.165	-1.030	<.001	<.001	3	10
SOFT_TISSUE	Flagellated sperm motility →	-0.081	-0.915	<.001	<.001	3	10
PANCREAS	Late endosome to vacuole transport →	+0.070	+0.542	<.001	<.001	3	10
PANCREAS	Microtubule depolymerization →	-0.168	-0.649	<.001	<.001	3	9
URINARY_TRACT	Golgi organization →	+0.051	+1.146	.001	.007	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,040 associations by consensus.

Sperm motility by PPCS expression — SOFT_TISSUE

Explore this box plot interactively →