PPBPP2

Across TCGA pan-cancer cohorts, PPBPP2 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated PPBPP2 data layer compared with 14 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher PPBPP2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PPBPP2 expression acts as an unfavorable survival marker.

SKCM and COAD are the cancer types where PPBPP2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.256	0.787	.008	12	view →
COAD	DFS	Median	All	0.184	0.689	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

PPBPP2–SKCM (OS)

Open the SKCM breakdown →