PPBPP2

Across TCGA patient cohorts, PPBPP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,712 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPBPP2-associated GO terms across cancer lineages are Methylation, Regulation of double-strand break repair, and Regulation of double-strand break repair via homologous recombination. Each is linked with PPBPP2 in more than 13 cancer types. Because this analysis shows association rather than direction, both PPBPP2-to-partner and partner-to-PPBPP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylation grouped by PPBPP2-low versus PPBPP2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPBPP2→partner) and Y-score (partner→PPBPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Methylation →	+0.060	+0.260	<.001	<.001	3	14
ESCA	Regulation of double-strand break repair →	+0.063	+0.245	<.001	<.001	3	13
STAD	Regulation of double-strand break repair via homologous recombination →	+0.061	+0.149	<.001	<.001	3	12
ESCA	rRNA metabolic process →	+0.078	+0.257	<.001	<.001	3	12
ESCA	Regulation of peptidyl-serine phosphorylation →	+0.035	+0.159	<.001	<.001	3	12
STAD	DNA conformation change →	+0.065	+0.157	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,712 associations by consensus.

Methylation by PPBPP2 expression — ESCA

Explore this box plot interactively →