PPBPP2

Across TCGA patient cohorts, PPBPP2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPBPP2-associated genes across cancer lineages are CD8+ Tcm and Chondrocytes. Each is linked with PPBPP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPBPP2-to-partner and partner-to-PPBPP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by PPBPP2-low versus PPBPP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPBPP2→partner) and Y-score (partner→PPBPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.048	+3.935	.003	.020	3	1
UCEC	Chondrocytes →	+0.019	+3.286	<.001	.045	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ Tcm by PPBPP2 expression — UCEC

Explore this box plot interactively →