PPBPP1

Across TCGA patient cohorts, PPBPP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,222 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPBPP1-associated GO terms across cancer lineages are Microtubule nucleation, Intrinsic apoptotic signaling pathway by p53 class mediator, and Autophagosome maturation. Each is linked with PPBPP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PPBPP1-to-partner and partner-to-PPBPP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule nucleation grouped by PPBPP1-low versus PPBPP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPBPP1→partner) and Y-score (partner→PPBPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Microtubule nucleation →	+0.107	+0.136	<.001	<.001	3	8
STAD	Intrinsic apoptotic signaling pathway by p53 class mediator →	+0.110	+0.122	<.001	<.001	3	7
STAD	Autophagosome maturation →	+0.105	+0.121	<.001	<.001	3	7
STAD	Microtubule polymerization →	+0.100	+0.153	<.001	<.001	3	7
STAD	Positive regulation of DNA metabolic process →	+0.112	+0.151	<.001	<.001	3	7
STAD	Vesicle localization →	+0.096	+0.140	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,222 associations by consensus.

Microtubule nucleation by PPBPP1 expression — STAD

Explore this box plot interactively →