Across TCGA patient cohorts, PPARA RNA expression is significantly associated with the protein abundance of many other proteins, with 11,451 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PPARA-associated proteins across cancer lineages are TTLL12, PCYT2, and PLXNB2. Each is linked with PPARA in more than 3 cancer types. Because this analysis shows association rather than direction, both PPARA-to-partner and partner-to-PPARA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPARA→partner) and Y-score (partner→PPARA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TTLL12 →	+0.516	+0.638	<.001	<.001	3	4
LSCC	PCYT2 →	+0.426	+0.528	<.001	<.001	3	4
GBM	PLXNB2 →	+0.256	+0.434	<.001	<.001	3	4
BRCA	MPP6 →	+0.438	+0.721	<.001	<.001	3	4
HNSC	SLC38A2 →	-0.823	-0.482	<.001	<.001	3	4
BRCA	VAV3 →	-0.294	-0.432	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,451 associations by consensus.

Exploration

PPARA survival (RNA) · tumor vs normal (RNA) · all PPARA data types