Across TCGA cell cohorts, PPARA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,842 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPARA-associated GO terms across cancer lineages are Peroxisome proliferator activated receptor signaling pathway, Macroautophagy, and Cytosolic transport. Each is linked with PPARA in more than 16 cancer types. Because this analysis shows association rather than direction, both PPARA-to-partner and partner-to-PPARA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPARA→partner) and Y-score (partner→PPARA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Peroxisome proliferator activated receptor signaling pathway →	+0.152	+1.340	.006	<.001	2	17
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.047	+0.784	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.088	+1.077	<.001	<.001	3	13
OVARY	Cellular response to insulin stimulus →	+0.038	+0.604	.002	.007	3	13
OVARY	Autophagy →	+0.049	+0.933	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.160	+0.846	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,842 associations by consensus.

Exploration

PPARA survival (RNA) · tumor vs normal (RNA) · all PPARA data types