PPA2

Across TCGA cell cohorts, PPA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,618 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PPA2-associated GO terms across cancer lineages are Box C/D sno(s)RNA metabolic process, Box C/D sno(s)RNA processing, and Box C/D sno(s)RNA 3'-end processing. Each is linked with PPA2 in more than 11 cancer types. Because this analysis shows association rather than direction, both PPA2-to-partner and partner-to-PPA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Box C/D sno(s)RNA metabolic process grouped by PPA2-low versus PPA2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPA2→partner) and Y-score (partner→PPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Box C/D sno(s)RNA metabolic process →	+0.089	+0.838	<.001	<.001	3	12
BLOOD_Myeloma	Box C/D sno(s)RNA processing →	+0.089	+0.838	<.001	<.001	3	12
BLOOD_Myeloma	Box C/D sno(s)RNA 3'-end processing →	+0.089	+0.838	<.001	<.001	3	12
PANCREAS	DAMP biosynthetic process →	+0.123	+0.511	.003	.005	2	10
PANCREAS	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.123	+0.511	.003	.005	2	10
BONE	Farnesyl diphosphate biosynthetic process →	+0.169	+0.708	.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,618 associations by consensus.

Box C/D sno(s)RNA metabolic process by PPA2 expression — BLOOD_Myeloma

Explore this box plot interactively →