Across TCGA patient cohorts, PP2D1 mutation is significantly associated with the RNA expression of many other genes, with 114 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PP2D1-associated genes across cancer lineages are RN7SL318P, LINC01050, and RPL23AP90. Each is linked with PP2D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PP2D1-to-partner and partner-to-PP2D1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PP2D1→partner) and Y-score (partner→PP2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL318P →	+0.241	+2.538	.004	.008	3	2
UCEC	LINC01050 →	+0.257	+3.151	.001	.001	3	1
UCEC	RPL23AP90 →	+0.382	+2.837	.004	.005	3	1
UCEC	ATF4P2 →	+0.048	+3.014	<.001	.004	3	1
UCEC	RN7SL478P →	+0.336	+2.939	<.001	.001	3	1
UCEC	GOLGA8F →	+0.021	+2.663	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 114 associations by consensus.

Exploration

PP2D1 survival (RNA) · tumor vs normal (RNA) · all PP2D1 data types