PP2D1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PP2D1 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PP2D1-associated genes across cancer lineages are Tuberin and Ku80. Each is linked with PP2D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PP2D1-to-partner and partner-to-PP2D1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PP2D1→partner) and Y-score (partner→PP2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTuberin →+0.487+2.817.003.03631
UCECKu80 →+0.345+2.820.017.03621
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration