Across TCGA cell cohorts, PP2D1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,640 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PP2D1-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Regulation of mRNA catabolic process, and Positive regulation of DNA repair. Each is linked with PP2D1 in more than 11 cancer types. Because this analysis shows association rather than direction, both PP2D1-to-partner and partner-to-PP2D1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PP2D1→partner) and Y-score (partner→PP2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Viral translational termination-reinitiation →	+0.063	+0.088	<.001	.001	3	12
LUNG_SCLC	Regulation of mRNA catabolic process →	+0.042	+0.108	.002	.002	3	11
OVARY	Positive regulation of DNA repair →	+0.051	+0.084	.001	.005	2	11
LUNG_SCLC	Regulation of mRNA stability →	+0.047	+0.104	.001	.003	3	10
BLOOD_Lymphoma	Positive regulation of double-strand break repair →	+0.053	+0.131	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.041	+0.075	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,640 associations by consensus.

Exploration

PP2D1 survival (RNA) · tumor vs normal (RNA) · all PP2D1 data types