POU6F2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POU6F2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,632 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POU6F2-associated genes across cancer lineages are CSF3R, TMEM97, and DNAJC27. Each is linked with POU6F2 in more than 3 cancer types. Because this analysis shows association rather than direction, both POU6F2-to-partner and partner-to-POU6F2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POU6F2 versus CSF3R in PDAC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU6F2→partner) and Y-score (partner→POU6F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACCSF3R →+1.163+0.654<.001.00134
LSCCTMEM97 →-0.979-0.519<.001<.00124
LSCCDNAJC27 →-0.300-0.374.009.00433
BRCADDX27 →-0.699-0.861.001.00233
LSCCZNF2 →-0.387-0.445<.001.00133
BRCANDUFAF7 →-0.502-0.784.008.00824
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,632 associations by consensus.

POU6F2 vs CSF3R — PDAC

Per-sample scatter of POU6F2 vs CSF3R in PDAC (Pearson r = 0.46).

Explore this scatter interactively →

Exploration