POU6F2

Across TCGA cell cohorts, POU6F2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,806 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible POU6F2-associated GO terms across cancer lineages are Translational initiation, Regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with POU6F2 in more than 11 cancer types. Because this analysis shows association rather than direction, both POU6F2-to-partner and partner-to-POU6F2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Translational initiation grouped by POU6F2-low versus POU6F2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POU6F2→partner) and Y-score (partner→POU6F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Translational initiation →	+0.103	+1.360	<.001	<.001	3	12
OESOPHAGUS	Regulation of myoblast fusion →	+0.129	+1.126	<.001	.001	3	11
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.124	+1.126	.001	.001	3	11
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.140	+1.126	.001	.001	3	10
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.138	+1.126	.001	.001	3	10
LUNG_NSCLC_LUSC	Calcium ion transport →	-0.072	-1.470	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,806 associations by consensus.

Translational initiation by POU6F2 expression — OESOPHAGUS

Explore this box plot interactively →