POU6F2-AS2

Across TCGA pan-cancer cohorts, POU6F2-AS2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated POU6F2-AS2 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher POU6F2-AS2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated POU6F2-AS2 expression acts as an unfavorable survival marker, although some lineages such as LUSC and ESCA show a favorable association.

STAD, KIRC, and BLCA are the cancer types where POU6F2-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.626	0.743	.004	56	view →
KIRC	DFS	Tertile	All	0.560	0.807	.002	51	view →
BLCA	DFS	Quartile	II,III,IV	0.238	0.428	.001	50	view →
KIRP	DFS	Tertile	All	0.711	0.921	<.001	42	view →
OV	OS	Quartile	All	0.794	0.875	<.001	42	view →
LUSC	OS	Median	II,III,IV	0.800	0.677	.006	35	view →
COAD	DFS	Quartile	II,III,IV	0.481	0.694	.001	29	view →
UCEC	OS	Quartile	All	0.812	0.891	.013	26	view →
ESCA	DFS	Tertile	All	1.000	0.441	.009	24	view →
LGG	OS	Tertile	All	0.338	0.476	.008	24	view →
ACC	DFS	Tertile	III,IV	0.126	0.478	.026	24	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

POU6F2-AS2–STAD (OS)

Open the STAD breakdown →