Across TCGA patient cohorts, POU6F1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,589 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POU6F1-associated proteins across cancer lineages are PRKG1, LUM, and SORBS3. Each is linked with POU6F1 in more than 7 cancer types. Because this analysis shows association rather than direction, both POU6F1-to-partner and partner-to-POU6F1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POU6F1→partner) and Y-score (partner→POU6F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRKG1 →	+0.800	+0.478	<.001	.003	3	8
COAD	LUM →	+0.848	+0.487	<.001	<.001	3	8
COAD	SORBS3 →	+0.348	+0.446	<.001	<.001	3	8
BRCA	SSC5D →	+0.801	+0.629	<.001	<.001	3	8
BRCA	PRELP →	+0.990	+0.590	<.001	<.001	3	7
BRCA	KANK2 →	+0.520	+0.649	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,589 associations by consensus.

Exploration

POU6F1 survival (RNA) · tumor vs normal (RNA) · all POU6F1 data types