POU5F2

Across TCGA cell cohorts, POU5F2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,393 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible POU5F2-associated GO terms across cancer lineages are Late viral transcription, mRNA splice site recognition, and Target-directed miRNA degradation. Each is linked with POU5F2 in more than 9 cancer types. Because this analysis shows association rather than direction, both POU5F2-to-partner and partner-to-POU5F2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Late viral transcription grouped by POU5F2-low versus POU5F2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POU5F2→partner) and Y-score (partner→POU5F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Late viral transcription →	+0.084	+0.022	.002	.002	3	10
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.162	+0.023	<.001	<.001	3	9
CNS	Target-directed miRNA degradation →	+0.057	+0.012	<.001	.003	3	9
SKIN	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.029	+0.013	.001	.007	3	8
UPPER_AERODIGESTIVE_TRACT	Viral transcription →	+0.126	+0.024	<.001	.004	3	8
BLOOD_Leukemia	Regulation of maintenance of sister chromatid cohesion →	+0.068	+0.025	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,393 associations by consensus.

Late viral transcription by POU5F2 expression — LARGE_INTESTINE

Explore this box plot interactively →