POU5F2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, POU5F2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible POU5F2-associated genes across cancer lineages are RBMY1J. Each is linked with POU5F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both POU5F2-to-partner and partner-to-POU5F2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1J grouped by POU5F2-low versus POU5F2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU5F2→partner) and Y-score (partner→POU5F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINRBMY1J →+0.006+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

RBMY1J by POU5F2 expression — SKIN

Box plot of RBMY1J in POU5F2-low vs POU5F2-high samples in SKIN.

Explore this box plot interactively →

Exploration