POU5F1P7

Across TCGA pan-cancer cohorts, POU5F1P7 RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated POU5F1P7 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher POU5F1P7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated POU5F1P7 expression acts as an unfavorable survival marker.

BLCA, LGG, and HNSC are the cancer types where POU5F1P7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.203	0.627	.011	45	view →
LGG	DFS	Tertile	All	0.452	0.834	<.001	33	view →
HNSC	DFS	Tertile	II,III,IV	0.163	0.695	.013	27	view →
STAD	OS	Tertile	III,IV	0.224	0.640	.021	18	view →
BRCA	OS	Tertile	II,III,IV	0.668	0.913	.015	18	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

POU5F1P7–BLCA (DFS)

Open the BLCA breakdown →