Across TCGA cell cohorts, POU5F1 RNA expression is significantly associated with the RNA expression of many other genes, with 6,555 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible POU5F1-associated genes across cancer lineages are PDZK1IP1, MMP7, and APOL1. Each is linked with POU5F1 in more than 6 cancer types. Because this analysis shows association rather than direction, both POU5F1-to-partner and partner-to-POU5F1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU5F1→partner) and Y-score (partner→POU5F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PDZK1IP1 →	+3.876	+2.110	<.001	<.001	3	7
OVARY	MMP7 →	+3.022	+1.800	<.001	<.001	3	6
URINARY_TRACT	APOL1 →	+2.521	+1.511	<.001	.002	2	6
STOMACH	SGK2 →	+3.082	+1.969	<.001	<.001	3	5
STOMACH	BAIAP2L2 →	+2.611	+1.430	<.001	<.001	3	5
STOMACH	BCO1 →	+1.586	+1.834	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,555 associations by consensus.

Exploration

POU5F1 survival (RNA) · tumor vs normal (RNA) · all POU5F1 data types