Across TCGA cell cohorts, POU5F1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,035 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible POU5F1-associated GO terms across cancer lineages are Cardiac cell fate determination, Endodermal cell fate commitment, and Endodermal cell fate specification. Each is linked with POU5F1 in more than 12 cancer types. Because this analysis shows association rather than direction, both POU5F1-to-partner and partner-to-POU5F1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POU5F1→partner) and Y-score (partner→POU5F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Cardiac cell fate determination →	+1.390	+2.088	<.001	<.001	3	13
STOMACH	Endodermal cell fate commitment →	-0.184	-1.507	<.001	.001	3	10
LIVER	Endodermal cell fate specification →	+1.877	+2.619	<.001	.006	3	8
LUNG_NSCLC_LUAD	Mammary gland development →	+0.063	+0.716	<.001	<.001	3	8
BREAST	Antigen processing and presentation of peptide antigen via MHC class I →	+0.134	+0.892	<.001	.002	3	7
BREAST	Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains →	+0.055	+1.226	<.001	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,035 associations by consensus.

Exploration

POU5F1 survival (RNA) · tumor vs normal (RNA) · all POU5F1 data types