POU4F1

Across TCGA patient cohorts, POU4F1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,979 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POU4F1-associated proteins across cancer lineages are TRIOBP, ITPRID2, and SNRNP200. Each is linked with POU4F1 in more than 3 cancer types. Because this analysis shows association rather than direction, both POU4F1-to-partner and partner-to-POU4F1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POU4F1 versus TRIOBP in GBM, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POU4F1→partner) and Y-score (partner→POU4F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIOBP →	-0.309	-1.014	<.001	<.001	3	4
BRCA	ITPRID2 →	-0.590	-0.377	.001	.006	3	4
LSCC	SNRNP200 →	+0.214	+0.480	<.001	<.001	3	3
COAD	SYTL1 →	-0.540	-0.180	.008	.002	2	4
BRCA	TNS1 →	-0.328	-0.349	<.001	<.001	3	3
LSCC	TNS1_S907 →	-0.505	-0.297	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,979 associations by consensus.

POU4F1 vs TRIOBP — GBM

Explore this scatter interactively →