Across TCGA patient cohorts, POU3F2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,196 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POU3F2-associated genes across cancer lineages are RPL12P30, CYTH4, and CRYBB1. Each is linked with POU3F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both POU3F2-to-partner and partner-to-POU3F2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU3F2→partner) and Y-score (partner→POU3F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL12P30 →	+1.031	+0.382	.002	.001	3	2
GBM	CYTH4 →	-0.533	-0.382	.001	<.001	3	1
GBM	CRYBB1 →	-0.467	-0.282	.001	<.001	3	1
GBM	SUN2 →	-0.373	-0.322	.004	<.001	3	1
GBM	AP1B1 →	-0.320	-0.227	.001	.005	3	1
GBM	APOBEC3H →	-0.411	-0.399	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,196 associations by consensus.

Exploration

POU3F2 survival (RNA) · tumor vs normal (RNA) · all POU3F2 data types