Across TCGA cell cohorts, POU3F2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible POU3F2-associated genes across cancer lineages are OR51I1, FKBP6, and MYF5. Each is linked with POU3F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both POU3F2-to-partner and partner-to-POU3F2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU3F2→partner) and Y-score (partner→POU3F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR51I1 →	+0.194	+3.192	<.001	.008	3	1
BLOOD_Lymphoma	FKBP6 →	+0.034	+3.321	<.001	.006	3	1
CNS	MYF5 →	+0.749	+5.321	<.001	.005	3	1
CNS	TAS2R7 →	+0.035	+4.981	<.001	.008	3	1
LUNG_NSCLC_LUAD	DPRX →	+0.328	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	NANOGNB →	+0.121	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

POU3F2 survival (RNA) · tumor vs normal (RNA) · all POU3F2 data types