Across TCGA cell cohorts, POU3F2 mutation is significantly associated with the mutation status of many other genes, with 622 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible POU3F2-associated genes across cancer lineages are XKR7, BICC1, and FAM50B. Each is linked with POU3F2 in more than 2 cancer types. Because this analysis shows association rather than direction, both POU3F2-to-partner and partner-to-POU3F2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU3F2→partner) and Y-score (partner→POU3F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	XKR7 →	+4.554	+4.247	.001	.001	1	3
STOMACH	BICC1 →	+3.584	+3.584	.006	.006	1	3
BLOOD_Lymphoma	FAM50B →	+4.969	+4.014	.008	.008	1	3
LARGE_INTESTINE	RRAGC →	+4.523	+5.087	.006	.006	1	3
CNS	GABBR1 →	+5.044	+5.614	.003	.003	1	2
CNS	LGR4 →	+4.044	+5.000	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 622 associations by consensus.

Exploration

POU3F2 survival (RNA) · tumor vs normal (RNA) · all POU3F2 data types