Across TCGA patient cohorts, POU3F1 mutation is significantly associated with the RNA expression of many other genes, with 356 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POU3F1-associated genes across cancer lineages are RNU6-18P, RN7SL542P, and MIR6842. Each is linked with POU3F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both POU3F1-to-partner and partner-to-POU3F1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU3F1→partner) and Y-score (partner→POU3F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-18P →	+0.513	+5.554	<.001	.004	3	2
LUAD	RN7SL542P →	+0.471	+6.584	<.001	.001	3	2
LUAD	MIR6842 →	+0.779	+5.044	<.001	.009	3	2
UCEC	COTL1P2 →	+0.282	+1.891	<.001	.004	3	2
UCEC	INTS4 →	+0.325	+3.119	.008	<.001	3	1
UCEC	KCTD14 →	+0.786	+1.939	.008	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 356 associations by consensus.

Exploration

POU3F1 survival (RNA) · tumor vs normal (RNA) · all POU3F1 data types