POU2F3

Across TCGA cell cohorts, POU2F3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,294 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible POU2F3-associated GO terms across cancer lineages are IMP biosynthetic process, Cellular response to indole-3-methanol, and Desmosome organization. Each is linked with POU2F3 in more than 9 cancer types. Because this analysis shows association rather than direction, both POU2F3-to-partner and partner-to-POU2F3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP biosynthetic process grouped by POU2F3-low versus POU2F3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POU2F3→partner) and Y-score (partner→POU2F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	IMP biosynthetic process →	-0.222	-2.500	<.001	<.001	3	10
OESOPHAGUS	Cellular response to indole-3-methanol →	+0.206	+1.166	.001	.003	3	9
STOMACH	Desmosome organization →	+0.446	+0.824	.008	.002	3	8
STOMACH	Plasma membrane organization →	+0.093	+1.131	.001	.001	3	8
OESOPHAGUS	Response to indole-3-methanol →	+0.189	+1.232	.001	.004	3	8
LUNG_NSCLC_LUAD	Regulation of blood-brain barrier permeability →	+0.275	+0.855	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,294 associations by consensus.

IMP biosynthetic process by POU2F3 expression — URINARY_TRACT

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